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five–four μmol/L selection,[156][157] the focus of serotonin in synaptic vesicles was calculated at 270 mM.[182] pursuing vesicular launch, the ensuing focus of serotonin from the synaptic cleft, to which serotonin receptors are exposed, is estimated for being about three hundred μmol/L. Hence, though in vitro receptor binding affinities, eff
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